منابع مشابه
Cytochemical and immunological aspects of the acute lymphocytic leukemias (as related to FAB classification).
The FAB classification of acute leukemias was proposed by a cooperative French-American-British group as an easily applied classification useful for uniform assessment of large clinical therapeutic trials. Although the classification is based on morphological criteria, cytochemical, biochemical, immunological and cytogenetic studies supplement the morphologic criteria for accurate identificatio...
متن کاملCytochemical Studies of Mitochondria
1. Mitochondria isolated from rat liver were disrupted with 0.3 per cent deoxycholate and a number of subfractions were isolated from this preparation by differential centrifugation. 2. The protein N, RNA and phospholipide content, as well as the succinoxidase, cytochrome c oxidase, adenylate kinase, and DPNH-cytochrome c reductase of these fractions were determined. 3. Two of these subfraction...
متن کاملClassification of Acute Leukemias
A useful classification of acute leukemia must be reproducible, must impart understanding of leukemogenesis and clinical behavior, and (most importantly) be clinically relevant, which makes such a classification indispensable for designing and comparing clinical trials. Classification systems by their very nature may influence the design of treatment regimens and may even bias investigations of...
متن کاملAcute leukemias of ambiguous origin.
OBJECTIVES This session of the Society for Hematopathology/European Association for Haematopathology Workshop focused on acute leukemias of ambiguous origin. METHODS We provide an overview of mixed-phenotype acute leukemia (MPAL) as recognized in the current World Health Organization classification and summarize diagnostic criteria for major categories of MPAL: B/myeloid, T/myeloid, B/T, and ...
متن کاملGenomic Characterization of Acute Leukemias
Over the past two decades, hematologic malignancies have been extensively evaluated due to the introduction of powerful technologies, such as conventional karyotyping, FISH analysis, gene and microRNA expression profiling, array comparative genomic hybridization and SNP arrays, and next-generation sequencing (including whole-exome sequencing and RNA-seq). These analyses have allowed for the ref...
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ژورنال
عنوان ژورنال: Acta Haematologica
سال: 1970
ISSN: 1421-9662,0001-5792
DOI: 10.1159/000208732